Prognostic system for clinical classification of liver disease using fuzzy cluster means

Authors

DOI:

https://doi.org/10.64497/jssci.34

Keywords:

prognosis, liver disease, classification, clinical decision, diagnostic system, fuzzy clustering

Abstract

Clinical management of liver diseases and severe disorders in liver tissue involves analysis of blood enzymes, usually from the blood count, as well as a functional test of the liver (LFT). The functional precision of the existing system is quite limited due to the complexity of clinical data and the lack of multi-class elements in decision support. In this study, quantitative and experimental designs were employed, incorporating fuzzy cluster means (Fuzzy-CM), for predictive segmentation of liver disorders as a data mining model. One thousand three hundred forty-five (1,345) instances of liver data were collected from the clinical repository. Experimental analysis of classifier (Fuzzy-CM) was done in matrix laboratory (MATLAB) and revealed that the classified clusters of over ninety percent (90%) of concerned patients (test cases) conform to fuzzy inference, which yielded improved precision and classification accuracy based on multi-class parameters of the clinical domain. Predictive projection was achieved through an intelligent classification model that handled the ambiguities of clinical data for decision support with 91.3% accuracy and 93.3% precision. The prognostic system, as a technological artifact, is recommended for adoption in the clinical management of liver diseases to facilitate the timely detection and implementation of therapeutic measures.

Downloads

Download data is not yet available.

References

[1] Arunim, G. & Mago, V. (2021). Role of machine learning in medical research: A survey. International Journal of Computer Science, 40, 70-76. DOI: https://doi.org/10.1016/j.cosrev.2021.100370

[2] Behera, M.P, Sarangi, A., Mishra, D. & Sarangi, S.K (2023). “A hybrid machine learning algorithm for heart and liver disease prediction using modified particle swarm optimization (PSO) with support vector machine (SVM)”. Proceedings of International conference in computing and information technology, 21, 18-27. DOI: https://doi.org/10.1016/j.procs.2023.01.062

[3] Cahyono, Y., Rosyani, P., Syah, F.S, Putri, F.S, Ashari, I., Sofian, K (2025). Liver disease classification using decision tree and random forest algorithm. International Journal of Integrative Sciences (IJIS), 4(1), 135-140. DOI: https://doi.org/10.55927/ijis.v4i1.13509

[4] Derarbhari, H. Asrani, S.K, Arab, J.P, Pose, I., & Kamath, P.S (2023). Global burden of liver disease. International Journal of Hepatol, 77, 16-37.

[5] Fan, Z, Chen, L, Li, J, Cheng, X, Yang, J, Tian, C, Zhang, Y, Huang, S., & Cheng, J. (2020). Clinical features of COVID-19-related liver damage. Clin Gastroenterol Hepatol. DOI: https://doi.org/10.1101/2020.02.26.20026971

[6] Gulia, A. & Vohra, R. (2024). Liver patient classification using intelligent techniques. International Journal of Computer Science and Information Technology, 6(9), 10-15.

[7] Gupta, K., Jiwani, N., Afreem, N., & Diryarani, D. (2022). “Liver disease prediction using machine learning classification techniques”, IEEE International Conference on Communication Systems and Network Technologies, (CSNT), 221-226. DOI: https://doi.org/10.1109/CSNT54456.2022.9787574

[8] Jian, W., Shu, S., Hong-Cui, C., & Lan-Juan, L. (2020). Liver diseases in COVID-19: Etiology, Treatment and Prognosis. World Journal of Gastroenterology, 26(19), 86–93. DOI: https://doi.org/10.3748/wjg.v26.i19.2286

[9] Khan, R.A, Luo, Y. & Wu, F.X (2022). “Machine learning based liver disease diagnosis: A systematic review. International Journal of Neuro computing, 468, 492-506. DOI: https://doi.org/10.1016/j.neucom.2021.08.138

[10] Mondal, D., Chowdhury, A. & Das, K. (2022). Epidemiology of liver disease in India, Journal of Cardiology and Disease Diagnosis, 19, 1-14. DOI: https://doi.org/10.1002/cld.1177

[11] Raddy, N.S & Preetham, P.S (2025). Liver disease prediction using machine learning and deep learning. International Journal of Engineering Science, 16(4), 64-70.

[12] Rani, R., Jaiswal, G., Nancy, L., Bhushan, S., Ullah, F., Singh, P. & Diwakar, M. (2025). Enhancing liver disease diagnosis with hybrid SMOTE-ENN balanced machine learning models – an empirical analysis of Indian patient liver disease datasets. International Journal of Frontiers in Medicine. DOI: https://doi.org/10.3389/fmed.2025.1502749

[13] Rakshith, D.B, Srivaskira, M., Kumar, A., & Gumraj, S.P (2021). Liver disease prediction system using machine learning techniques. International Journal of Engineering Research and Technology, 10(9), 49-74.

[14] Rajabi, M., Sadeghizadeh, H., Mola-Amini, Z., & Ahmadyrad, N. (2019). Hybrid adaptive neuro fuzzy inference system for diagnosing the liver disorders. International Journal of Computer Engineering, 5(2), 37-44. Retrieved from http:// www.iosrjournals.org

[15] Shashidhar, K.N, & Krishna, S.N (2019). Pros and cons existing biomarkers for cirrhosis of liver. Journal of Scientific Medical Sciences, 3(6), 63-72.

[16] Tokala, S., Hajarathaiah, K., Gunda, S.R, Botla, S., Nalluri, L., Nagamanohar, P., Anamalamudi, S., & Enduri, M.K (2023). Liver disease prediction and classification using machine learning techniques. International Journal of Advanced Computer Science and Applications, 14(2), 871-878 DOI: https://doi.org/10.14569/IJACSA.2023.0140299

[17] Veeranki, S.K & Varshmay, M. (2022). Intelligent techniques and comparative performance analysis of liver disease prediction. International Journal of Mechanical Engineering, 7, 489-503.

[18] Zhou, P, Yang, X.L, Wang, X.G., Hu, B, Zhang, L, Zhang, W., & Zheng, G.F. (2020). A pneumonia outbreak associated with a new coronavirus of probable bat origin. Journal of Pathology and Nature. 270–273. DOI: https://doi.org/10.1038/s41586-020-2951-z

[19] Zahra, S.B, Athar, A., Khan, M.A, Abbas, S., & Ahmad, G. (2019). Automated diagnosis of liver disorder using multilayer neuro fuzzy. International Journal of Advanced and Applied Sciences. 6(2), 23-32. Retrieved from http://www.science-gate.com/IJAAS.html DOI: https://doi.org/10.21833/ijaas.2019.02.005

[20] Zhang, X., Zhao, H., Zhang, S., & Li, R. (2019). A novel deep neural network model for multi-label chronic disease prediction. 10(351). DOI: https://doi.org/10.3389/fgene.2019.00351

Downloads

Published

2025-09-05

How to Cite

Ayeni, A. G. (2025). Prognostic system for clinical classification of liver disease using fuzzy cluster means. Journal of Statistical Sciences and Computational Intelligence, 1(3), 187–197. https://doi.org/10.64497/jssci.34
Views
  • Abstract 252
  • PDF 106

Similar Articles

1 2 > >> 

You may also start an advanced similarity search for this article.